Shopping Cart
no products
[<<] [<] [>] [>>] 29 Products in this category

Filamin (smooth muscle, turkey) - 2x100 µg

Cat. #:
8312-01
Shipping:
FedEx Express (Global) FedEx Express (Global) (shipping info)
Quantity:
2x100 µg

 


Filamin
(Actin Binding Protein)


Cat. #: 8312-01  

........................................................................................................................................................................................................................................................................................................................................................................................................................................................


 Description

 

 

Protein

Filamin (Filamin A)

Origin

Smooth muscle, turkey

Molecular mass

546kDa

Protein description

Filamin from turkey gizzard is a homodimer (2x273kDa) with a molecular mass of 546kDa, consisting of 24 repeats of ~96 amino acids and an N-terminal actin binding sequence. Filamin crosslinks actin filaments into orthogonal networks.

The C-terminal end of each Filamin monomer is characterized by a hinge region, responsible for the flexibility of actin networks. 

Actin interaction

Actin cross linking protein. Kd actin-binding = 0.5µM.



Properties

 

 

Form

Lyophilized, ready-to-use.

Quantity per unit

2x100µg

Buffer

10mM NaCl, 20mM Tris pH 7.4, 0.5mM DTT and 2.4% disaccharides, when reconstituted with 100 µl ultrapure water to obtain a 1mg/ml solution.

Purity

>98% by scanning densitometry from Coomassie G-250 stained SDS-Gels.

Purification notes

Purified from turkey gizzard muscle.

Protein concentration

Determined by OD280 (0.1%=0.64).

Storage instructions

Upon reconstitution the product is stored on ice. This product can also be stored as a glycerol stock at -20°C. Avoid repeated freeze / thaw cycles.

Shipping conditions 

At ambient temperature. Upon delivery store at -70°C.

Remarks

For Use in Research only. Not for Use in Human or Veterinary Diagnostical or Therapeutical Applications. 

CAS no.

 





Further Information


Product DataSheet

Material and Safety Data Sheet

Protein Sequence on NCBI



 

References

Real-time dynamics of emerging actin networks in cell-mimicking compartments.
Deshpande S, Pfohl T.; ​PLoS One. 2015 Mar 18;10(3):e0116521. doi: 10.1371/journal.pone.0116521. eCollection 2015.

 


 

 

Related products:

Actin (rabbit skeletal muscle alpha actin) 4x250µg

Actin (rabbit skeletal muscle alpha actin) 4x250µg

from 134,00 EUR
ATTO532-Actin (alpha-Actin skeletal muscle, rabbit) - 2x100µg

ATTO532-Actin (alpha-Actin skeletal muscle,...

176,00 EUR
Customers who bought this product bought also the following products:

Gelsolin TL40 (N-terminal cytoplasmic gelsolin) - 50µg

Gelsolin TL40 (N-terminal cytoplasmic gelsolin)...

249,00 EUR
Actin (rabbit skeletal muscle alpha actin) 4x250µg

Actin (rabbit skeletal muscle alpha actin) 4x250µg

from 134,00 EUR
ATTO488-Actin (alpha-Actin skeletal muscle, rabbit) - 2x100µg

ATTO488-Actin (alpha-Actin skeletal muscle,...

176,00 EUR