Hypermol® specializes in the purification and controlled modification of actins and actin-binding proteins. We offer custom preparation from native tissue as well as synthesis of protein conjugates tailored to your experimental readout.
If your workflow requires a specific dye, labeling chemistry, degree of labeling range, or application constraints (e.g., microscopy brightness and photostability), we can discuss feasibility and prepare a conjugate optimized for your project goals.
Interaction readouts • microscopy-to-assay support
Our facilities support a range of approaches to characterize protein interactions—from microscopy-based visualization to biochemical and biophysical readouts. If you want to validate an interaction, compare conditions, or establish an assay baseline, we can recommend a suitable analysis path.
Microscopy
Epifluorescence
TIRFM
Transmission electron microscopy
Biochemical assays
Co-sedimentation analyses
Analytical gel filtration
Limited proteolysis
ELISA
SDS-PAGE / IEF / 2D-PAGE / Western / Dot blot
Biophysical analyses
High-precision fluorometry (incl. 96–384 well formats)
Some research applications require specific solution conditions for actin and actin ligands. We prepare custom buffers to match your experimental system—including defined ion compositions (e.g., EGTA/Mg2+ systems), lipid-compatible conditions, or project-specific pH and ionic strength targets.
All buffers are prepared using analytical grade chemicals in ultrapure water, aligned with the preparation standards used across Hypermol® products.
