Actin-Toolkit Electron Microscopy

 
Actin-Toolkit Electron Microscopy
Negative-stain TEM
G-Actin & F-Actin
Ready-to-use specimen preparation
 
Hypermol Actin-Toolkit Electron Microscopy
Structural analysis of actin assemblies
From monomers to filament networks
Negative-stain electron microscopy enables direct structural visualization of actin and ligand-induced actin assemblies.
Structural actin imaging by TEM

Visualize G-actin, filaments, bundles & networks

A ready-to-use toolkit for negative-stain transmission electron microscopy of actin and actin–ligand assemblies.

The Hypermol® Actin-Toolkit Electron Microscopy is designed for molecular imaging of ligands interacting with monomeric G-actin or filamentous F-actin. Negative-stain TEM provides direct structural information on individual actin filaments as well as ligand-induced filament bundles, higher-order assemblies and actin networks.

The toolkit provides defined actin preparations and specimen-preparation reagents for maintaining either the G-actin or F-actin state during sample preparation. It supports structural assessment of ligand-dependent changes in actin organization and can be used to examine filament morphology, length, thickness and higher-order architecture.

Structural imaging
Molecular visualization of monomeric actin, filaments, bundles and networks by TEM.
Ligand effects
Assess structural effects of actin-binding ligands on filament organization and assembly.
Morphometry
Determine filament length, thickness and structural properties of actin assemblies.
Browse Electron Microscopy Toolkits
Negative-stain specimen preparation
The toolkit contains actin-compatible G- and F-actin buffers, MgCl2, SpreadingSolution, filtration units and a detailed experimental handbook for preparation of negatively stained electron microscopy specimens.
Native actin variants
Available with rabbit skeletal muscle α-actin or bovine cardiac α-actin.
Typical applications
Visualization of G-actin and F-actin, structural analysis of ligand-bound actin, filament morphology and morphometry, filament bundling, higher-order actin assemblies and actin network formation.
Accessible EM workflow
Designed for researchers performing specimen preparation after introductory EM training or supplying prepared samples to an electron microscopy facility.
Hypermol Actin-Toolkit Electron Microscopy
Direct structural analysis of actin organization.
The Actin-Toolkit Electron Microscopy combines native actin, defined G- and F-actin preparation conditions and specimen-preparation reagents for negative-stain TEM analysis.
Hypermol Satisfaction Guarantee
Validated product quality with Satisfaction Guarantee.
Actin products from Hypermol® are prepared and quality controlled for reliable biochemical and structural analysis of actin interactions.
 
Kit Electron Microscopy skeletal actin
Actin-Toolkit Electron Microscopy (rabbit skeletal muscle alpha-actin)
  • Molecular imaging analysis of ligands bound to monomeric actin or actin filaments, bundles or networks by TEM;
  • Determination of length, thickness or properties of actin filaments;
428,00 EUR
excl. Shipping costs
Kit Electron Microscopy cardiac actin
Actin-Toolkit Electron Microscopy (bovine alpha-cardiac actin)
  • Molecular imaging analysis of ligands bound to monomeric actin or actin filaments, bundles or networks by TEM;
  • Determination of length, thickness or properties of actin filaments;
498,00 EUR
excl. Shipping costs
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