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Ezrin

ERM-family protein

Membrane-actin linker

Human recombinant, untagged

Membrane meets actin

Pure Ezrin protein for studying cell cortex organization, adhesion, migration and actin-rich membrane structures.

Mediator of cell adhesion and migration

Ezrin protein for membrane-cytoskeleton linkage and cell surface dynamics

Human recombinant, untagged Ezrin for studying actin-to-membrane coupling, epithelial surface organization and migration-associated cytoskeletal remodeling.

Ezrin is an ERM-family actin-binding protein that links the cortical actin cytoskeleton to the plasma membrane. It is a key organizer of actin-rich membrane domains and is especially relevant for epithelial microvilli, membrane ruffles, cell cortex mechanics, adhesion and motility.

Hypermol^® Ezrin is supplied as pure human recombinant untagged protein, amino acids 1-568, with an apparent molecular mass of approximately 70 kDa. It is suited for biochemical assays, reconstituted actin-membrane systems and mechanistic studies of how cells organize membrane protrusions and connect surface architecture to actin dynamics.

Cortex linkage

Connects actin organization with plasma membrane architecture and cell surface structure.

Microvilli & ruffles

Useful for studying actin-rich epithelial structures, apical polarity and dynamic membrane protrusions.

Migration biology

Supports research on adhesion, cell spreading, motility and cortical remodeling.

Browse Ezrin protein

For actin-membrane reconstitution

Use Ezrin in defined systems to investigate how cortical actin networks connect to membrane-associated structures and shape cell surface architecture.

For epithelial cell biology

Ezrin is highly relevant for studies of microvilli formation, apical membrane organization, polarity and membrane ruffling in epithelial models.

For adhesion and migration research

Because Ezrin couples actin remodeling to membrane behavior, it is useful for studying cell spreading, cortical mechanics and migration-related surface dynamics.

Strong experimental use cases

Study actin-to-membrane coupling in defined biochemical assays.

Model microvilli and apical membrane organization.

Investigate membrane ruffle formation and cortical remodeling.

Analyze adhesion, cell spreading and migration-associated actin dynamics.

Combine Ezrin with actin, lipids or binding partners in reconstituted systems.

Probe ERM-family mechanisms in epithelial polarity and surface architecture.

Product focus

Pure Ezrin protein, human recombinant untagged, amino acids 1-568, Mw approximately 70 kDa, for assays investigating cytoskeleton-to-membrane linkage, cell adhesion and migration-associated membrane dynamics.

Validated product quality with Satisfaction Guarantee.
Proteins from Hypermol^® are of validated high biological activity, as described in our publications.