The Secret of Flexibility.  


Filamin from turkey gizzard is a homodimer, consisting of 24 repeats of ~96 amino acids and an N-terminal actin binding sequence.
Filamin crosslinks actin filaments into orthogonal networks.

The C-terminal end of each Filamin monomer is characterized by a hinge region, responsible for the flexibility of actin networks. 

Proteins from Hypermol are of validated high biological activity, as described in our publications. 

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